• MaxQ Technical Services

MaxQ’s Non-Dry Ice Shipper for Freshly Frozen Plasma (FFP)

It is no surprise that shipping freshly frozen plasma (FFP < -18℃) is a costly and challenging proposition. The current industry standard Styrofoam and cardboard dry ice shippers are prone to temperature excursions, damaged frozen plasma units, require multiple SOPs for seasonal pack-outs, occupy a large amount of storage space, and provide limited reuse. Shipping plasma requires a hefty amount of dry ice per shipment, which results in bulky packaging and higher costs. Not to mention the hazards and specialized training required to handle dry ice. Sublimation of dry-ice creates empty space inside the shipper, generating voids which inadvertently increase the chances of the frozen plasma units from cracking / breaking due to physical impact during transport. This can lead to up to 40% loss of FFP during shipment as reported in literature1.

The MaxPlus Plasma Shipper is an evolutionary solution that employs reusable phase change coolant packs to eliminate the dependence on dry-ice for shipping FFPs.

The form stabilized phase change coolant packs enable a quick to pack, error-proof, all-season pack-out that is proven to work for over 24 hours. The highly reusable MaxPlus shippers are up to 30% smaller than the industry standard dry ice shippers. This means that a major reduction of shipping costs is possible due to their reduced size and the removal of major dry ice shipping limitations. Blood centers and hospitals can experience the following benefits:

Proven MaxPlus protection – eliminates undesired breakage of FFP units

Turn-key validated pack-out for six to nine units

24 hour, all-season performance – singular SOP

Uses reusable phase change coolant pack

COVID-19, Convalescent Plasma – Major strain on Plasma distribution

Blood centers and hospitals across the globe are experiencing major challenges in sourcing blood and blood components, such as FFP, because of the current pandemic. One of the most successful weapons in this fight against the pandemic is COVID-19 Convalescent Plasma (CCP), which is collected, stored and transported similar to FFP. In the last American Association of Blood Banks survey (conducted Dec. 14-16)2, 82.4% of responding hospitals in the U.S. transfused CCP units in the last few weeks. Nearly 18% hospitals are reporting delays in obtaining CCP units. With skyrocketing positive COVID-19 cases across the world, the demand for CCP is increasing by the hour. To further complicate the situation, international logistics systems are choked by the COVID-19 vaccine distribution, which also uses significant quantities of dry ice. As demand gets higher, reservation of large aircraft for vaccine distribution and their replacement with smaller aircraft has limited the transport of shipments packed with dry ice. Smaller aircrafts are permitted by the FAA to fly with only 5 lbs. or less of dry ice at a time. Even if there were exceptions, the overall capacity is much lower and results in an inefficient supply chain. Our non-dry ice FFP/CCP shippers aim to restore the efficiency that has been lost.


  1. Pusateri, A.E., et al., The need for dried plasma–a national issue. Transfusion, 2019. 59(S2): p. 1587-1592.


To find out more about how your blood center or hospital can benefit from MAXQ’s advanced packaging, visit

MaxPlus Blood Shippers for Plasma, pRBCs and Platelets